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. 2022 Sep 27;12:16104. doi: 10.1038/s41598-022-20050-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Vactosertib blocks radiation-induced ROS markers. (a, b) Protein expression of PRDX1, NRF2, HO-1 in 4T1-Luc cells (a) and MDA-MB-231 cells (b) by western blot analysis (Band was normalized by GAPDH.). The band image was cropped after selecting a representative blot, and the sample was derived from the same experiment. Original blots are presented in Supplementary Fig. 1. (c) mRNA expression of Nrf2, Ho-1, and Nqo-1 in 4T1-Luc cells (Relative mRNA expression was normalized by Ppia.).