Figure 1.

Clinical outcomes after IL-2 discontinuation. Each patient is represented by a horizontal bar with the time on low-dose IL-2 (LD IL-2) represented in orange and the time after IL-2 discontinuation represented in blue. The majority of the patients were able to discontinue all immunosuppression after stopping LD IL-2, but 3 patients (case numbers 10, 11, and 14) had progression of chronic GVHD requiring initiation of additional immunosuppression and 3 patients (case numbers 2, 8, and 18) continued on their prior immunosuppressive agents at the time of last follow up. Time to discontinuation of prednisone is represented as gray bars if prednisone was stopped after IL-2 discontinuation. If prednisone was weaned off during the IL-2 treatment course, the time of discontinuation is represented by a gray triangle. The time to discontinuation of all immunosuppression (IS) is represented as yellow bars and yellow stars. ECP, extracorporeal photopheresis; f/u, follow up; no., number; pred, prednisone; Tx, treatment.