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. 2022 Sep 14;9:974722. doi: 10.3389/fmolb.2022.974722

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Copyright © 2022 Xin, Mao, Cui, Li, Chen, Li, Tu, Liu, Wang, Wang, Liu, Song and Song.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Somatic variants of the CRGscore-defined groups. (A,B) Mutation spectrum of the top 20 mutated genes. (C) Survival analysis of the TMB-defined groups. (D) The relevance of TMB with CRGscore was revealed through the correlation analysis.