Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Strategies to redirect T cells toward tumor cells using TCRs and CARs. T cells can be redirected against TAAs via viral transduction of specific T Cell Receptors (TCRs) or Chimeric Antigen Receptors (CARs), which identify target molecules in the surface of tumor cells independently of MHCI presentation. LTR, Long Terminal Repeat; Fab, fragment antigen-binding region; TM, transmembrane domain.
