Figure 7.

Luteolin and PI3K/AKT inhibitor reduce the production of aqueous extract PM2.5-induced ICAM-1. H460 cells were pretreated with luteolin (30 µM) or LY294002 (20 µM) for 1 h following stimulated with PM2.5 (100 µg/ml) for 24 h. ELISA was performed to detect the ICAM-1 production. Cells without PM2.5 stimulation and agent administration were used as the control group (mock). Quantitative data are presented as the mean ± SEM of the experiments (n = 3). *P < 0.05, significant compared to the mock group.