Table 1. Baseline characteristics of the study population.
| Characteristics | Statin non-user | Statin user |
|---|---|---|
| No. of patients | 6,275,524 | 74,876 |
| Age (yr) | 30.8±5.0 | 34.5±3.9 |
| Sex (male) | 3,705,715 (59.1) | 62,556 (83.6) |
| BMI (kg/m2) | 22.96±3.59 | 26.23±3.93 |
| Systolic BP (mmHg) | 117.62±13.14 | 125.53±14.76 |
| Diastolic BP (mmHg) | 73.7±9.42 | 79.36±10.72 |
| Fasting glucose (mg/dL) | 90.67±15.94 | 107.73±43.7 |
| eGFR (mL/min/1.73 m2) | 96.1±49.6 | 92.7±54.3 |
| Baseline TC (mg/dL) | 184.3±35.8 | 219.3±52.9 |
| Baseline HDL-C (mg/dL) | 57.8±27.6 | 52.2±43.0 |
| Baseline TG (mg/dL) | 96.1 (96.0–96.1) | 186.1 (185.3–187.0) |
| Baseline LDL-C (mg/dL) | 102 (84–122) | 120 (87–158) |
| Current smoker | 2,177,566 (34.7) | 34,281 (45.8) |
| Alcohol drinking* | 549,285 (8.75) | 10,477 (14.0) |
| Regular exercise† | 802,702 (12.8) | 11,661 (15.6) |
| Income (lower 25%) | 1,357,336 (21.6) | 12,137 (16.2) |
| Diabetes mellitus | 107,711 (1.7) | 14,873 (19.9) |
| Hypertension | 438,053 (7.0) | 27,810 (37.1) |
Data are expressed as the means±standard deviation, median (25–75%), or number (%). The p-values for the trend were <0.001 for all variables because of the large size of the study population.
BMI, body mass index; BP, blood pressure; eGFR, estimated glomerular filtration rate; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol.
*Individuals who consumed ≥30 g of alcohol per day were defined as alcohol drinking.
†Regular exercise was defined as >30 minutes of moderate physical activity performed ≥5 times per week or >20 minutes of strenuous physical activity performed ≥3 times per week.