Table 2.
Patient characteristics of COVID-19 cohort 2.
| Variables | COVID-19 group | P value | ||
|---|---|---|---|---|
| Mild (n = 65) | Severe (n = 218) | Critical (n = 115) | ||
| Gender (male) | 31 (47.7) | 135 (61.9) | 81 (70.4) | <0.0001 |
| Age (years) | 52 (43.5-64.0) | 59 (49.0-68.0) | 72 (63.5-76.5) | <0.0001 |
| COVID-19-Mortality | 0 (0) | 1 (0.5) | 41 (35.7) | <0.0001 |
| Comorbidities | ||||
| Obesity | 11 (16.9) | 64 (29.4) | 29 (25.2) | <0.0001 |
| Metabolic syndrome | 4 (6.2) | 15 (6.9) | 20 (17.4) | <0.0001 |
| Diabetes mellitus | 9 (13.8) | 34 (15.6) | 32 (27.8) | <0.0001 |
| Hypertension | 21 (32.3) | 83 (38.1) | 60 (52.2) | <0.0001 |
| Cardiovascular disease | 7 (10.8) | 19 (8.7) | 15 (13.0) | <0.0001 |
| Biochemical parameters | ||||
| D-Dimer | 533.0 (339.8-937.3) | 565.5 (397.0-849.8) | 896.0 (577.8-1474.5) | <0.0001 |
| Fibrinogen | 641.0 (522.8-813.0) | 765.0 (658.0-863.8) | 784.0 (682.0-900.3) | <0.0001 |
| IL-6 | 11.4 (4.2-44.9) | 9.1 (3.0-19.7) | 25.5 (8.2-73.6) | <0.0001 |
| Ferritin | 429.0 (232.0-637.0) | 445.5 (257.8-860.0) | 550.0 (371.0-1098.0) | n.s. |
| CRP | 3.9 (1.0-8.2) | 7.0 (3.5-11.5) | 10.4 (4.8-16.9) | <0.0001 |
| Glucose | 106.0 (89.0-114.5) | 104.0 (87.0-130.0) | 122.0 (99.0-161.0) | <0.0001 |
| Creatinine | 0.8 (0.7-1.0) | 0.8 (0.6-1.0) | 0.9 (0.7-1.1) | 0.008 |
Data are presented as n (%) and median (25th and 75th interquartile range) for qualitative and quantitative variables, respectively. IL, interleukin; CRP, C-reactive protein. n.s., non-significant.