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. 2022 Sep 14;13:991662. doi: 10.3389/fimmu.2022.991662

Table 3.

Correlations between EBNA-1 and VCA IgG titers with different clinical variables in the samples collected before DMT onset in the MS group.

Starting Age Disease duration EDSS Relapses 2-years before DMT onset ARR
EBNA-1 IgG titers r 0.131 –0.116 –0.107 –0.153 –0.073
p 0.018 0.036 n.s. 0.006 n.s.
VCA IgG titers r 0.113 0.067 0.075 –0.106 –0.102
p 0.041 n.s. n.s. n.s. n.s.

Correlations were assessed by using the Spearman’s rank correlation coefficient (r). Bold values indicates the statistically significant values after Bonferroni correction (p<0.007); significant p values prior Bonferroni correction are also shown. ARR, annualized relapse rate (number of relapses since the beginning of the disease/duration of the disease [years]). n.s., not significant.