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. 2022 Sep 14;13:991662. doi: 10.3389/fimmu.2022.991662

Table 4.

EBNA-1 and VCA IgG titers at baseline visit (prior DMT onset) and progression, number of relapses, clinical response and therapeutic failure after two years of follow-up with DMT.

EBNA-1 IgG VCA IgG
PROGRESSION PROGRESSION
pos./N (%) Titers* pos./N (%) Titers*
YES 51/53 (96.2) 25.7 53/53 (100) 59.1
NO 265/270 (98.1) 25.3 269/270 (99.6) 59.9
p** n.s. n.s. n.s. n.s.
OR (95% CI)
RELAPSES RELAPSES
pos./N (%) Titers* pos./N (%) Titers*
YES 128/131 (97.7) 25.5 130/131 (99.2) 60.1
NO 190/194 (97.9) 25.3 194/194(100) 59.4
p** n.s. n.s. n.s. n.s.
OR (95% CI)
CLINICAL RESPONSE CLINICAL RESPONSE
pos./N (%) Titers* pos./N (%) Titers*
YES 165/168 (98.2) 25.3 168/168 (100) 59.7
NO 153/157 (97.5) 25.5 156/157 (99.4) 59.9
p** n.s. n.s. n.s. n.s.
OR (95% CI)
THERAPEUTIC FAILURE THERAPEUTIC FAILURE
pos./N (%) Titers* pos./N (%) Titers*
YES 92/94 (97.9) 25.6 94/94 (100) 59.0
NO 226/231 (97.8) 25.2 230/231 (99.6) 60.1
p** n.s. n.s. n.s. n.s.
OR (95% CI)

*Median values of the arbitrary units (AU). **Student t test (for titers) and Chi-square test (for categorical variables). n.s., not significant.