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. 2022 Sep 14;9:913661. doi: 10.3389/fcvm.2022.913661

Table 3.

Effects of ESZWD on cardiac function of CHF-HKYd rats.

IVSd/mm LVIDd/mm LVPWd/mm IVSs/mm LVIDs/mm SV/mL LVEF% FS% LVPWs/mm E/A
Normal 1.213 ± 0.29 5.288 ± 0.52 1.650 ± 0.37 2.538 ± 0.86 2.363 ± 0.81 0.3138 ± 0.09 88.64 ± 9.03 57.53 ± 15.98 1.685 ± 0.25 1.542 ± 0.15
Model 1.643 ± 0.27# 6.129 ± 0.33# 1.671 ± 0.22 2.243 ± 0.38 3.757 ± 0.70## 0.3929 ± 0.07 73.55 ± 12.7## 38.73 ± 9.89## 1.891 ± 0.10 0.729 ± 0.12#
ESZWD-L 2.033 ± 0.58 5.633 ± 0.25* 2.000 ± 0.36 3.067 ± 0.25 3.433 ± 0.67 0.3100 ± 0.09* 76.99 ± 16.0 38.65 ± 13.4 2.667 ± 0.45 1.863 ± 0.43*
ESZWD-M 1.817 ± 0.57 5.450 ± 0.63* 2.017 ± 0.38 2.767 ± 0.30 2.900 ± 0.87* 0.3183 ± 0.08 82.41 ± 9.61 47.66 ± 12.2 3.033 ± 0.66** 2.013 ± 0.42*
ESZWD-H 1.433 ± 0.12 6.133 ± 0.80 1.733 ± 0.35 2.367 ± 0.23 3.60 ± 0.56 0.4767 ± 0.22 84.37 ± 8.85 49.65 ± 12.4 2.933 ± 0.68* 1.976 ± 0.36*
Benazepril 1.800 ± 0.62 5.950 ± 1.28 1.900 ± 0.67 3.425 ± 0.88 2.350 ± 0.72** 0.4950 ± 0.25 92.30 ± 4.09** 60.31 ± 8.10** 3.525 ± 0.79** 1.794 ± 0.28*

Compared with control group,

#P < 0.05,

##P < 0.01, difference has significance; Compared with model group,

*P < 0.05,

**P < 0.01, difference has significance.