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. 2022 Sep 14;10:935243. doi: 10.3389/fpubh.2022.935243

Table 4.

Factors associated with the intention to receive a third COVID-19 vaccine dose (n = 638).

Intention to receive a third COVID-19 dose Adjusted OR
(95% CI)
p-value
Factor Yes
(n = 269)
No
(n = 369)
Age group (years)
 18–34 (reference group) 80 (30.8) 180 (69.2)
 35–44 142 (47.5) 157 (52.5) 1.61 (1.09–2.38) 0.017
 55+ 47 (59.5) 32 (40.5) 1.92 (1.06–3.49) 0.032
Sex
 Female (reference group) 163 (40.8) 237 (59.2)
 Male 106 (44.5) 132 (55.5) 1.04 (0.71–1.53) 0.822
Cohort
 First (R1-R10) 63 (31.7) 136 (68.3)
 Second (R10 “top-up”) 206 (46.9) 233 (53.1) 2.04 (1.36–3.10) 0.001
Smoking status
 Non-smoker (reference group) 236 (41.0) 340 (59.0)
 Smoker 33 (53.2) 29 (46.8) 2.21 (1.22–4.03) 0.009
Experienced any adverse effects 1
 No (reference group) 109 (55.3) 88 (44.7)
 Yes 160 (36.3) 281 (63.7) 0.52 (0.35–0.77) 0.001
Constructs of vaccine hesitancy2 (median, IQR)
 Confidence 5.3 (4.0–6.0) 4.0 (3.3–5.0) 1.54 (1.30–1.84) <0.001
 Complacency 3.3 (2.3–4.0) 4.0 (3.0–4.3) 0.85 (0.71–1.01) 0.070
 Constraint 2.7 (2.0–4.0) 3.7 (2.7–4.0) 0.82 (0.69–0.98) 0.027
 Calculation 5.7 (4.7–6.0) 5.3 (4.3–6.0) 0.94 (0.77–1.14) 0.536
 Collective 5.7 (4.7–6.3) 4.7 (4.0–5.7) 1.30 (1.04–1.64) 0.023

1From the first and/or second COVID-19 vaccine dose.

2Average scores of items within each construct were computed, with higher scores indicating higher levels of the constructs. Cronbach's alpha values for the 5 constructs ranged from 0.72 - 0.87.OR,Odds ratio; CI, Confidence interval. Bold figures indicate p-values smaller than 0.05.