TABLE 2.
Power for standard GEMMA, GEMMA LOCO, and subpopulation meta-analysis applied to the two simulation settings with cis effects in the 43 strain simulations. Power is the proportion of genes with at least one nonzero cis-SNP effect that had at least one cis-SNP with a significant association identified by the corresponding model.
Method | Power: One cis effect | Power: Multiple cis effects |
---|---|---|
Standard GEMMA | 0.67 | 0.63 |
GEMMA LOCO | 0.68 | 0.64 |
Subpop Meta | 0.50 | 0.47 |