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Drought stress upregulates MdRFNR1-1 gene expression by promoting the binding of MdSUVH1/3 and MdDNAJ1/2 to the methylated MITE insertion upstream of MdRFNR1-1. Subsequently, MdRFNR1 is involved in a cascade of redox reactions that scavenge excess ROS generated during drought stress. Reprinted from Niu et al. (2022), Figure 11.
