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. 2022 Sep 14;12:897476. doi: 10.3389/fonc.2022.897476

Table 3.

Univariate and multivariate analysis of CSS for the matched cohort after PSM.

Characteristic Univariate Multivariate
P-value OR 95% CI P-value OR 95% CI
Year of diagnosis 0.903
 2004–2007 1
 2009–2011 0.838 0.952 0.592–1.530
 2012–2015 0.651 0.875 0.490–1.562
Gender
 Male 1 1
 Female 0.056 0.491 0.237–1.018 0.148 0.574 0.270–1.219
Age groups (years) 0.554
 ≤50 1
 51–60 0.617 1.223 0.556–2.694
 61–70 0.657 1.188 0.555–2.546
 ≥71 0.215 1.715 0.732–4.021
Race
 White 1
 Black and others 0.177 0.537 0.218–1.325
cT classification 0.001 0.002
 T1 1 1
 T2 0.650 0.807 0.320–2.034 0.454 0.697 0.270–1.797
 T3 0.034 2.127 1.058–4.276 0.083 1.880 0.921–3.838
 T4 0.002 5.201 1.843–14.676 0.009 4.107 1.420–11.875
 Tx 0.647 0.617 0.078–4.874 0.423 0.424 0.052–3.455
cN classification 0.001 0.004
 N0 1 1
 N1 0.176 1.407 0.857–2.310 0.269 1.330 0.802–2.206
 N2 0.003 2.285 1.318–3.962 0.010 2.116 1.195–3.748
 N3 < 0.001 4.859 2.003–11.789 0.002 4.134 1.688–10.127
Tumor histology
 Adenocarcinoma 1 1
 SCC 0.031 0.428 0.198–0.926 0.129 0.538 0.242–1.198
Histological grade 0.410
 Well 1
 Moderate 0.380 1.902 0.453–7.989
 Poor/Undifferentiated 0.406 1.821 0.443–7.487
 Unknown 0.156 3.037 0.655–14.071
PORT
 Yes 1
 No 0.494 1.164 0.754–1.797

T, tumor; N, nodal; SCC, squamous cell carcinoma; PORT, postoperative radiotherapy.