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. Author manuscript; available in PMC: 2023 Jan 14.
Published in final edited form as: ACS Infect Dis. 2021 Dec 22;8(1):227–241. doi: 10.1021/acsinfecdis.1c00553

Figure 1.

Figure 1.

(A) Chemical structure of lead compounds 12, and the most active compound 3 in the second generation; (B) approaches to improving the activity of this scaffold of compounds.