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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Ann Surg. 2020 Nov 17;275(6):1165–1174. doi: 10.1097/SLA.0000000000004427

TABLE 4.

Results of Univariate Analysis of csRFS and rPFS for Margin Variables

csRFS rPFS
Variables n (%) or mean (SD) Events (n) HR (95% Cl) P Events (n) HR (95% Cl) P
Margin variables within positive margin (n = 90)
No. of dysplastic foci, mean (SD) 2.47 (2.15) 12 1.07 (0.84–1.35) 0.58 15 1.16 (0.99–1.38) 0.07
 Missing 15 (16.67)
Size largest dysplasia, cm, mean (SD) 0.31 (0.29) 13 3.69 (1.09–12.46) 0.04 16 2.41 (0.53–10.84) 0.25
 Missing 13 (14.44)
Main Duct involvement
 No 48 (53.33) 7 1 8 1
 Yes 18 (20) 4 1.47 (0.43–5.06) 0.54 4 1.61 (0.48–5.37) 0.44
 Missing 24 (26.67)
Highest grade of dysplasia
 Low/intermediate 85 (94.44) 13 1 20 1
 High 4 (4.44) 3 3.68 (1.04–12.97) 0.04 2 3.65 (0.83–15.98) 0.09
 Missing 1 (1.11)

Patients with negative margin were not considered in the univariate analysis. Missing data were not included in the analysis.

SD indicates standard deviation.