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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Ann Surg. 2020 Nov 17;275(6):1165–1174. doi: 10.1097/SLA.0000000000004427

TABLE 7.

Previous Publications on IPMN Recurrence (Sort by Year)

Authors Year Study Type IPMN Cohort No. of Cases Definition of Margin Positivity Margin Positive Margin Positivity Risk Factor for Recurrence Median Follow-Up
White et al14 2007 SC Noninvasive 78 Any grade of dysplasia; PanIN 3 (only) explicitly included 29.5% (n = 23) Yes 40 months
Park et al15 2011 SC Unselected 103 Any grade of dysplasia including invasive carcinoma 4.9% (n = 5) No 26.7 months
Mariya and Traverso16 2012 SC Unselected 203 Any grade of dysplasia including invasive carcinoma 6.9% (n = 14) No 40 months
He et al5 2013 SC Noninvasive 130 Not explicitly stated 20% (n = 26) No 38 months
Frankel et al9 2013 SC Noninvasive 192 Any grade of dysplasia; PanIN explicitly included 45% (n = 86) Yes 46 months
Kang et al17 2014 SC Unselected 366 Any grade of dysplasia 17.8% (n = 65) No 44.4 months
Marchegiani et al6 2015 SC Unselected 381 Any grade of dysplasia including invasive carcinoma 15.5% (n = 59) Yes 58 months*
Marchegiani et al18 2015 SC Main duct 173 High-grade dysplasia or invasive carcinoma only 9.8% (n = 17) Yes 56 months*
Yamaguchi et al19 2016 SC Unselected 55 Not explicitly stated 29.1% (n = 16) No 2.3 years
Dhar et al20 2018 MC (8) Noninvasive 330 Any grade of dysplasia; PanIN explicity included 19.7% (n = 65) No 36 months
Al Efishat et al22 2018 SC Noninvasive +microinvasive (≤10 mm of invasive component) 319 Any grade of dysplasia including invasive carcinoma; PanIN explicitly included 50.8% (n = 162) No 42 months
Hirono et al21 2020 MC (11) Unselected 1074 High-grade dysplasia or invasive IPMC; PanIN 3 (only) explicitly included Not reported No 54.2 months
Our study 2020 SC Noninvasive 126 Any grade of dysplasia; PanIN explicitly included 71.4% (n = 90) No 114 months

MC indicates multicenter (number of institutions); SC, single-center.

*

Follow-up of survivors only.