Figure 4.

Incident indeterminate solid nodule: low-grade PanIN lesion. EUS and microscopic images from a familial pancreatic cancer relative who developed a 5-mm hypoechoic nodule in the tail (A). EUS-fine needle aspiration performed at 2 separate visits showed atypical cells. EUS-guided tattooing was performed to localize the lesion for surgical resection and histologic evaluation. Distal pancreatectomy with pathology examination of the specimen revealed a focal cluster of multiple low-grade PanIN with adjacent fibrosis (B), corresponding to the location of the preoperative tattoo.