Table 2.
Number of patients (%) | Risk of ATE (%) | Sensitivity | Specificity | PPV | NPV | Odds ratios vs low risk | |
---|---|---|---|---|---|---|---|
Derivation cohort | |||||||
Low risk (0-8) | 1431 (40.6%) | 4.5 | – | – | – | – | – |
Intermediate risk (9–13) | 1909 (54.1%) | 20.1 | 0.86 | 0.47 | 0.20 | 0.96 | 5.36 |
High risk (14+) | 186 (5.3%) | 53.8 | 0.61 | 0.94 | 0.54 | 0.96 | 24.84 |
Validation cohort | |||||||
Low risk (0–8) | 748 (31.3%) | 2.4 | – | – | – | – | – |
Intermediate risk (9–13) | 1375 (57.5%) | 12.8 | 0.91 | 0.38 | 0.13 | 0.98 | 5.95 |
High risk (14+) | 269 (11.2%) | 33.8 | 0.83 | 0.80 | 0.34 | 0.98 | 20.73 |
ATE, arterial thromboembolism; NPV, negative predictive value; PPV, positive predictive value.