. 2022 Oct 1;18(10):2377–2385. doi: 10.5664/jcsm.10114

Table 5.

Multivariable analysis of the association of sleep architecture and gas exchange with spirometry variables, asthma medications, and BMI in obese children with asthma.

	SE (%)^a	AAI^a	% Time in N1^a	% Time in N2	% Time in N3	% Time in REM Sleep	PLMI^a	Baseline O₂ Saturation^a	O₂ Saturation Nadir^a	Baseline ETCO₂^a	Peak ETCO₂^a
FEV₁	1.00, 0.78	1.01, 0.34	1.00, 0.71	−0.08, 0.39	0.05, 0.55	−0.03, 0.50	1.00, 0.89	1.00, 0.24	0.99, 0.04	0.99, 0.69	0.99, 0.36
FVC	0.99, 0.41	1.00, 0.47	1.00, 0.38	0.11, 0.26	−0.18, 0.05	0.06, 0.23	0.99, 0.66	1.00, 0.11	1.00, < 0.001	1.00, 0.96	1.00, 0.67
ICS	0.04, 0.34	1.01, 0.87	0.90, 0.35	3.14, 0.10	−0.14, 0.94	−1.09, 0.30	0.84, 0.47	0.99, 0.03	1.02, 0.37	1.02, 0.37	0.98, 0.51
Montelukast	1.06, 0.06	0.92, 0.31	1.03, 0.77	−2.94, 0.08	2.63, 0.11	0.37, 0.69	1.22, 0.36	1.01, 0.11	0.98, 0.49	0.94, 0.01	0.97, 0.10
BMI	1.00, 0.02	1.01, 0.16	1.02, 0.001	0.24, 0.006	−0.41, < 0.001	−0.13, 0.007	1.02, 0.13	0.99, < 0.001	1.00, < 0.001	1.00, 0.47	1.00, 0.36
OSA	0.99, 0.78	1.31, < 0.001	1.34, 0.001	−2.62, 0.08	0.72, 0.62	−0.29, 0.73	0.70, 0.006	1.00, 0.39	0.93, < 0.001	1.04, 0.09	1.05, 0.002

For all variables, the β coefficient, or ^aits geometric mean for log-transformed variables and corresponding P value are reported. AAI = arousal and awakening index, BMI = body-mass index, ETCO₂ = end-tidal carbon dioxide, FEV₁ = forced expiratory volume, FVC = forced vital capacity, ICS = inhaled corticosteroids, OSA = obstructive sleep apnea, PLMI = periodic limb movement index, REM = rapid eye movement, SE = sleep efficiency.