. 2022 Aug 31;2(9):2152–2161. doi: 10.1021/jacsau.2c00413

Table 3. Dinitration of Arenes with 2o^a^,^b.

graphic file with name au2c00413_0009.jpg

Standard conditions III: 3 (1.0 equiv), 2o (3.0 equiv), In(OTf)₃ (20 mol %), HFIP (0.5 M), and 80 °C.

All reactions were performed on a 0.2 mmol scale. Isolated yields were reported.

4.0 equiv of 2o was used.

5.0 mmol scale.

The mononitrated product 1-bromo-3-methoxy-2-methyl-4-nitrobenzene (5q′) was also formed in a 36% yield.

2.0 equiv of 2o was used.

Table 3. Dinitration of Arenes with 2oa,b.