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. 2022 Sep 28;21:186. doi: 10.1186/s12943-022-01651-4

Fig. 6.

Fig. 6

The inhibition of LUAD cell migration, invasion, and endothelial-to-mesenchymal transition. A549 and NCI-H1299 cells were treated with REMAIN or si-ADAM9 for 48 h. The mRNA (A) and protein (B) levels of ADAM9 in A549 and NCI-H1299 cells treatment with REMAIN, respectively. (C) Wound healing assays measured cell migration. (D) Transwell assays measured cell invasion. (E) Western blot assays determined the expression of EMT markers E-cadherin, N-cadherin, and Vimentin. *, P < 0.05; **, P < 0.01; ***, P < 0.001