Table 5. Multivariable analysis for overall survival.

ECOG, Eastern Cooperative Oncology Group; HR, hazard ratio; CI, confidence interval; Ref, reference

*Analysis was done using a reference level of no lung, bone, and brain metastasis.

Variable	HR (95% CI)	p-value
Stage II (ref = stage I)	0.671 (0.15-3.07)	0.61
Stage III (ref = stage I)	5.065 (1.02-25.27)	0.048
Stage IV (ref = stage I)	5.968 (0.55-64.47)	0.14
Hormonal therapy (ref = no)	0.142 (0.02-1.17)	0.07
Radiation therapy (ref = no)	3.626 (0.71-18.60)	0.12
ECOG 1 (ref = ECOG 0)	3.141 (1.00-9.88)	0.05
ECOG 2 (ref = ECOG 0)	24.736 (1.92-318.73)	0.014
ECOG 3 (ref = ECOG 0)	1.704 (0.18-16.48)	0.65
*Lung metastasis (ref = no)	42.102 (7.20-246.36)	<0.001
*Bone metastasis (ref = no)	0.052 (0.01-0.48)	0.009
*Brain metastasis (ref = no)	8.453 (1.88-38.04)	0.005