Table 3.

Standard regression coefficient and hazard ratio for each predictor in the clinical model and the radiographic model in the MOST training dataset (n=2658)

		Clinical model		Radiographic model
		β′	Standard HR (95% CI)	β′	Standard HR (95% CI)
Age, years
	<55	..	1 (ref)	..	1 (ref)
	55–59	0·55	1·73 (1·08–2·80)	0·54	1·71 (1·06–2·77)
	60–64	0·91	2·49 (1·62–3·83)	0·63	1·88 (1·22–2·89)
	65–69	1·04	2·83 (1·83–4·39)	0·63	1·87 (1·21–2·89)
	70–74	1·28	3·61 (2·30–5·66)	0·62	1·85 (1·19–2·90)
	≥75	1·01	2·75 (1·62–4·65)	0·12	1·13 (0·67–1·90)
Sex
	Male	..	1 (ref)	..	1 (ref)
	Female	0·14	1·14 (1·01–1·3)	0·22	1·24 (1·09–1·42)
Race
	White	..	1 (ref)	..	1 (ref)
	Non-White	−0·64	0·53 (0·36–0·77)	−0·85	0·43 (0·3–0·61)
History of knee arthroscopy
	No	..	1 (ref)	..	..
	Yes	0·23	1·26 (1·15–1·38)	..	..
Frequent knee pain
	No	..	1 (ref)	..	1 (ref)
	Yes	0·45	1·56 (1·28–1·92)	0·31	1·36 (1·11–1·66)
Use of analgesics
	No	..	1 (ref)	..	1 (ref)
	Yes	0·25	1·29 (1·13–1·47)	0·25	1·29 (1·13–1·47)
Use of glucosamine
	No	..	1 (ref)	..	..
	Yes	0·23	1·25 (1·13–1·39)	..	..
Body-mass index		0·27	1·31 (1·18–1·46)	..	..
WOMAC pain score		0·47	1·59 (1·41–1·80)	0·30	1·35 (1·19–1·54)
Kellgren-Lawrence grade
	0	..	..	..	1 (ref)
	1	..	..	0·82	2·26 (0·79–6·5)
	2	..	..	1·97	7·19 (3·13–16·5)
	3	..	..	3·20	24·5 (11·4–52·9)
	4	..	..	3·99	54·3 (25·1–117·5)

β′ was estimated from standardised variables. The standard HR was calculated using Cox regression from standardised variables. β′=standard regression coefficient. HR=hazard ratio. WOMAC=Western Ontario and McMaster Universities Osteoarthritis Index. MOST=Multicenter Osteoarthritis Study.