Figure 6.
Histological evaluation of SC35M infection rate. Murine lungs were either pre-treated with the solvent DMSO (control), 20 µM fluoxetine (8 h), or with 500 U/mL IFN-α (8 h) prior to infection with 105 PFU/ mL SC35M for 24 h. Representative images of lung tissue sections stained for viral NP. Scatter plot representation of the total area covered by NP-positive cells. Data showing single lungs, with means ± SEM superimposed. Statistically significant differences were detected by Kruskal-Wallis test and Dunn's multiple comparisons test, * p < 0.1, ** p < 0.01, **** p < 0.0001, n = 5 murine lungs/group, scale bar 50 µm.