Figure 6.

Magnetic iron oxide and silica based NPs loaded with various drugs presented essential antibacterial activity against Gram-negative pathogenic bacteria. Briefly, bacteria (1 × 10⁶) were incubated with different drugs conjugated with ZnO-NPs and nanoparticle alone at 37°C for 2 h. Next, the cultures were ten-fold serially diluted and plated onto the nutrient agar plates and the plates were incubated for overnight at 37°C and counted the viable bacterial colonies on the following day. For negative control, bacteria were incubated in PBS alone whereas for positive control gentamicin (100 µg/mL) was used. The data are expressed as the means ± standard errors from several independent experiments performed in duplicate where (*) represent when P ≤ 0.05