Skip to main content
. 2022 Aug 24;19(17):10528. doi: 10.3390/ijerph191710528

Table A1.

Available toxicity and emission data.

Compound NTP Nr. Species Route 90-Day Study Available? Relative Organ Weights Emission Data? Source *
o-Cresol TOX 9 Rat and mouse Feed Yes Liver, kidney, and thymus Yes Schaller/
St. Helen/
Forster
1,3-Butadiene TR 434 Mouse Inhalation No - Yes Schaller/
St. Helen/
Forster
2,3-Butanedione TR 593 Rat and mouse Inhalation Yes Liver, kidney, and thymus Yes Forster
2,6-Dimethylanaline TR 278 Rat Gavage Yes Liver Yes Forster
Acetone TOX 3 Rat Water Yes Liver and kidney Yes Schaller/
St. Helen/
Forster
Acrolein TOX 48 Rat and mouse Gavage Yes Liver, kidney, and thymus Yes Schaller/
St. Helen/
Forster
Acrylamide TR 575 Rat and mouse Drinking water or feed Yes Liver Yes Schaller/
St. Helen/
Forster
Acrylonitrile TR 506 Mouse Gavage Yes Liver, kidney, and thymus Yes Schaller/
St. Helen/
Forster
Allyl alcohol TOX 48 Rat and mouse Gavage Yes Liver, kidney, and thymus Yes Forster
Benzene TR 289 Rat Gavage No - Yes Schaller/
St. Helen/
Forster
Benzo(b)furan TR 370 Rat and mouse Gavage Yes None Yes Forster
Benzyl alcohol TR 343 Rat and mouse Gavage Yes None Yes St. Helen
Butyrolactone TR 406 Rat and mouse Gavage Yes Liver, kidney, and thymus Yes St. Helen
Cadmium oxide TOX 39 Rat and mouse Inhalation Yes Liver, kidney, and thymus Yes Schaller/
St. Helen/
Forster
Chromium TR 546/TOX 72 Rat and mouse Drinking water Yes Liver, kidney, and thymus Yes Schaller/
St. Helen/
Forster
Cobalt TR 581 Rat and mouse Inhalation Yes Liver, kidney, and thymus Yes Schaller/
Forster
Copper TOX 29 Rat and mouse Drinking water and feed Yes Liver, kidney, and thymus Yes Schaller/
Forster
Ethyl carbamate TR 510/
TOX 52
Rat and mouse Drinking water Yes Liver, kidney, and thymus Yes Forster
Ethyl benzene TR 466/
TOX 10
Rat and mouse Inhalation Yes Liver, kidney Yes Forster
Ethylene glycol TR 413 Mouse Feed Yes Liver, kidney, and thymus Yes Forster
Ethylene oxide TR 326 Mouse Inhalation Yes Liver Yes Schaller/
St. Helen/
Forster
Furan TR 402 Rat and mouse Gavage Yes Liver, kidney, and thymus Yes Forster
Furfural TR 382 Rat and mouse Gavage Yes Liver, kidney, and thymus Yes St. Helen
Glycidol TR 374 Rat and mouse Gavage Yes None Yes St. Helen/
Forster
Hydroquinone TR 366 Mouse Gavage Yes Liver Yes Schaller/
St. Helen/
Forster
Isobutyraldehyde TR 472 Rat and mouse Inhalation Yes Liver, kidney, and thymus Yes Schaller/
Forster
Isoprene TOX 31 Rat and mouse Inhalation Yes Liver, kidney, and thymus Yes Schaller/
St. Helen/
Foster
Naphthalene TR 500/TR 410 Rat and mouse Inhalation No - Yes Forster
Nickel oxide TR 451 Rat and mouse Inhalation Yes Liver, kidney, and thymus Yes Schaller/
St. Helen/
Forster
Nitromethane TR 461 Rat and mouse Inhalation Yes Liver, kidney, and thymus Yes Forster
Toluene TR 371 Mouse Inhalation and gavage Yes Liver, kidney Yes Schaller/Forster
Phenol TR 203 Rat and mouse Drinking water Yes None Yes Schaller/
St. Helen/
Forster
Propylene oxide TR 267 Rat and mouse Inhalation Yes None Yes Schaller/
St. Helen/
Forster
Pyridine TR 470 Rat and mouse Drinking water Yes Liver, kidney, and thymus Yes Schaller/
St. Helen/
Forster
Resorcinol TR 403 Rat and mouse Gavage Yes Liver, kidney, and thymus Yes Schaller/
Forster
Styrene TR 185 Rat and mouse Gavage Yes None Yes Schaller/
St. Helen/
Forster

* Schaller refers to [50]; St. Helen refers to [8]; Forster refers to [51].