Table A1.
Compound | NTP Nr. | Species | Route | 90-Day Study Available? | Relative Organ Weights | Emission Data? | Source * |
---|---|---|---|---|---|---|---|
o-Cresol | TOX 9 | Rat and mouse | Feed | Yes | Liver, kidney, and thymus | Yes | Schaller/ St. Helen/ Forster |
1,3-Butadiene | TR 434 | Mouse | Inhalation | No | - | Yes | Schaller/ St. Helen/ Forster |
2,3-Butanedione | TR 593 | Rat and mouse | Inhalation | Yes | Liver, kidney, and thymus | Yes | Forster |
2,6-Dimethylanaline | TR 278 | Rat | Gavage | Yes | Liver | Yes | Forster |
Acetone | TOX 3 | Rat | Water | Yes | Liver and kidney | Yes | Schaller/ St. Helen/ Forster |
Acrolein | TOX 48 | Rat and mouse | Gavage | Yes | Liver, kidney, and thymus | Yes | Schaller/ St. Helen/ Forster |
Acrylamide | TR 575 | Rat and mouse | Drinking water or feed | Yes | Liver | Yes | Schaller/ St. Helen/ Forster |
Acrylonitrile | TR 506 | Mouse | Gavage | Yes | Liver, kidney, and thymus | Yes | Schaller/ St. Helen/ Forster |
Allyl alcohol | TOX 48 | Rat and mouse | Gavage | Yes | Liver, kidney, and thymus | Yes | Forster |
Benzene | TR 289 | Rat | Gavage | No | - | Yes | Schaller/ St. Helen/ Forster |
Benzo(b)furan | TR 370 | Rat and mouse | Gavage | Yes | None | Yes | Forster |
Benzyl alcohol | TR 343 | Rat and mouse | Gavage | Yes | None | Yes | St. Helen |
Butyrolactone | TR 406 | Rat and mouse | Gavage | Yes | Liver, kidney, and thymus | Yes | St. Helen |
Cadmium oxide | TOX 39 | Rat and mouse | Inhalation | Yes | Liver, kidney, and thymus | Yes | Schaller/ St. Helen/ Forster |
Chromium | TR 546/TOX 72 | Rat and mouse | Drinking water | Yes | Liver, kidney, and thymus | Yes | Schaller/ St. Helen/ Forster |
Cobalt | TR 581 | Rat and mouse | Inhalation | Yes | Liver, kidney, and thymus | Yes | Schaller/ Forster |
Copper | TOX 29 | Rat and mouse | Drinking water and feed | Yes | Liver, kidney, and thymus | Yes | Schaller/ Forster |
Ethyl carbamate | TR 510/ TOX 52 |
Rat and mouse | Drinking water | Yes | Liver, kidney, and thymus | Yes | Forster |
Ethyl benzene | TR 466/ TOX 10 |
Rat and mouse | Inhalation | Yes | Liver, kidney | Yes | Forster |
Ethylene glycol | TR 413 | Mouse | Feed | Yes | Liver, kidney, and thymus | Yes | Forster |
Ethylene oxide | TR 326 | Mouse | Inhalation | Yes | Liver | Yes | Schaller/ St. Helen/ Forster |
Furan | TR 402 | Rat and mouse | Gavage | Yes | Liver, kidney, and thymus | Yes | Forster |
Furfural | TR 382 | Rat and mouse | Gavage | Yes | Liver, kidney, and thymus | Yes | St. Helen |
Glycidol | TR 374 | Rat and mouse | Gavage | Yes | None | Yes | St. Helen/ Forster |
Hydroquinone | TR 366 | Mouse | Gavage | Yes | Liver | Yes | Schaller/ St. Helen/ Forster |
Isobutyraldehyde | TR 472 | Rat and mouse | Inhalation | Yes | Liver, kidney, and thymus | Yes | Schaller/ Forster |
Isoprene | TOX 31 | Rat and mouse | Inhalation | Yes | Liver, kidney, and thymus | Yes | Schaller/ St. Helen/ Foster |
Naphthalene | TR 500/TR 410 | Rat and mouse | Inhalation | No | - | Yes | Forster |
Nickel oxide | TR 451 | Rat and mouse | Inhalation | Yes | Liver, kidney, and thymus | Yes | Schaller/ St. Helen/ Forster |
Nitromethane | TR 461 | Rat and mouse | Inhalation | Yes | Liver, kidney, and thymus | Yes | Forster |
Toluene | TR 371 | Mouse | Inhalation and gavage | Yes | Liver, kidney | Yes | Schaller/Forster |
Phenol | TR 203 | Rat and mouse | Drinking water | Yes | None | Yes | Schaller/ St. Helen/ Forster |
Propylene oxide | TR 267 | Rat and mouse | Inhalation | Yes | None | Yes | Schaller/ St. Helen/ Forster |
Pyridine | TR 470 | Rat and mouse | Drinking water | Yes | Liver, kidney, and thymus | Yes | Schaller/ St. Helen/ Forster |
Resorcinol | TR 403 | Rat and mouse | Gavage | Yes | Liver, kidney, and thymus | Yes | Schaller/ Forster |
Styrene | TR 185 | Rat and mouse | Gavage | Yes | None | Yes | Schaller/ St. Helen/ Forster |