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. Author manuscript; available in PMC: 2022 Sep 28.
Published in final edited form as: Methods Mol Biol. 2022;2483:297–317. doi: 10.1007/978-1-0716-2245-2_19

Table 1.

PKA inhibitor compounds for modulation of PKA-mediated signaling

PKA inhibitors Mechanism of action
PKI peptide Blocks the catalytic site of PKA
H89 ATP-competitive inhibitor of PKA
Rp-cAMPS Prevents cAMP binding to R-subunits
AT13148 Clinical candidate broad PKA/AGC kinase inhibitor