Table 1.
PKA inhibitors | Mechanism of action |
---|---|
PKI peptide | Blocks the catalytic site of PKA |
H89 | ATP-competitive inhibitor of PKA |
Rp-cAMPS | Prevents cAMP binding to R-subunits |
AT13148 | Clinical candidate broad PKA/AGC kinase inhibitor |
PKA inhibitors | Mechanism of action |
---|---|
PKI peptide | Blocks the catalytic site of PKA |
H89 | ATP-competitive inhibitor of PKA |
Rp-cAMPS | Prevents cAMP binding to R-subunits |
AT13148 | Clinical candidate broad PKA/AGC kinase inhibitor |