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. Author manuscript; available in PMC: 2022 Sep 28.
Published in final edited form as: Methods Mol Biol. 2022;2483:297–317. doi: 10.1007/978-1-0716-2245-2_19

Table 2.

Classical cAMP-stimulating agents for activation of PKA signaling-complexes

cAMP-stimulating agents Mechanism of action
Forskolin Activates adenylyl cyclases
IBMX Inhibits PDEs
Isoproterenol Indirectly activates adenylyl cyclases
PGE2 Indirectly activates adenylyl cyclases
DB-cAMP Activates PKA