Table 1.

Crosswalk table to compare coverage of Human Infection with 2019 Novel Coronavirus Case Report form fields and ELR^a, the CCDA^b, and FHIR^c.

CDCd PUIe form field		Covered in CCDA	Covered in ELR	Covered in FHIR	Covered in other data sources
What is the current status of this person?
	PUI: testing pendingf	Yes (lab test and result information)	N/Ag	Yes	N/A
	PUI: tested negativef	Yes (lab test and result information)	N/A	Yes	N/A
	Presumptive case (positive local test): confirmatory testing pending	N/A	N/A	N/A	N/A
	Presumptive case (positive local test): confirmatory tested negative	N/A	N/A	N/A	N/A
	Laboratory-confirmed case	Yes	Yes	Yes	N/A
	Report date of PUI to CDC	N/A	N/A	N/A	N/A
	Report date of case to CDC	N/A	N/A	N/A	N/A
	County of residence	Yes	Yes	Yes	N/A
	State of residence	Yes	Yes	Yes	N/A
	Ethnicity	Yes	Yes	Yes	N/A
	Race	Yes	Yes	Yes	N/A
	Sex	Yes	Yes	Yes	N/A
	Date of birth	Yes	Yes	Yes	N/A
	Age	Yes	Yes	Yes	N/A
Was the patient hospitalized? Date?		Yes	N/A	Yes	ADTh or Census data
Was the patient admitted to the ICUi?		N/A	N/A	Yes	ADT or Census data
Did the patient receive mechanical ventilation (MV) or intubation? Days of MV?		N/A	N/A	N/A	Custom report
Did the patient receive extracorporeal membrane oxygenation (ECMO)?		N/A	N/A	N/A	Custom report
Did the patient die as a result of this illness? Date?		Yes	N/A	Yes	ADT
Date of first positive specimen collection		Yes	Yes	Yes	N/A
Did the patient develop pneumonia?		Yes	N/A	Yes	N/A
Did the patient have acute respiratory distress syndrome?		Yes	N/A	Yes	N/A
Did the patient have another diagnosis/etiology for their illness?		N/A	N/A	N/A	N/A
Did the patient have an abnormal chest X-ray?		N/A	N/A	Yesf	N/A
Symptoms present during course of illness: (symptomatic/asymptomatic/unknown)		N/A	N/A	N/A	N/A
Symptom onset date		N/A	N/A	N/A	N/A
Symptom resolution date		N/A	N/A	N/A	N/A
Is the patient a health care worker in the United States?		N/A	N/A	N/A	N/A
Does the patient have a history of being in a health care facility (as a patient worker or visitor) in China?		N/A	N/A	N/A	N/A
In the 14 days prior to illness onset, did the patient have any of the following exposures (check all that apply)?
	Travel to Wuhan	N/A	N/A	N/A	N/A
	Travel to Hubei	N/A	N/A	N/A	N/A
	Travel to mainland China/other non-US country	N/A	N/A	N/A	N/A
	Community contact with another lab-confirmed COVID-19 case	N/A	N/A	N/A	N/A
	Any health care contact with another lab-confirmed COVID-19 case (patient/visitor/health care worker [HCW])	N/A	N/A	N/A	N/A
	Exposure to a cluster of patients with severe acute lower respiratory distress of unknown etiology	N/A	N/A	N/A	N/A
	Household contact with another lab- confirmed COVID-19 case	N/A	N/A	N/A	N/A
	Animal exposure	N/A	N/A	N/A	N/A
	If the patient had contact with another COVID-19 case, was this person a US case?	N/A	N/A	N/A	N/A
Under what process was the PUI or case first identified (check all that apply)?
	Clinical evaluation leading to PUI determination	N/A	N/A	Yesf	N/A
	Contact tracing of the patient	N/A	N/A	N/A	N/A
	Routine surveillance	N/A	N/A	N/A	N/A
	Epidemic Information Exchange (EpiX) notification of travelers, if checked	N/A	N/A	N/A	N/A
	Unknown	N/A	N/A	N/A	N/A
	Other (specify)	N/A	N/A	N/A	N/A
Symptoms
	Fever >100.4°F (38°C)	N/A	N/A	Yesf	N/A
	Subjective fever (felt feverish)	N/A	N/A	Yesf	N/A
	Chills	N/A	N/A	Yesf	N/A
	Muscle aches (myalgia)	N/A	N/A	Yesf	N/A
	Runny nose (rhinorrhea)	N/A	N/A	Yesf	N/A
	Sore throat	N/A	N/A	Yesf	N/A
	Cough (new onset or worsening of chronic cough)	N/A	N/A	Yesf	N/A
	Shortness of breath (dyspnea)	N/A	N/A	Yesf	N/A
	Nausea or vomiting	N/A	N/A	Yesf	N/A
	Headache	N/A	N/A	Yesf	N/A
	Abdominal pain	N/A	N/A	Yesf	N/A
	Diarrhea (≥3 loose/looser-than-normal stools/24-hour period)	N/A	N/A	Yesf	N/A
	Other	N/A	N/A		N/A
Pre-existing medical conditions
	Chronic lung disease (asthma/emphysema/chronic obstructive pulmonary disease [COPD])	Yes	N/A	Yes	N/A
	Diabetes mellitus	Yes	N/A	Yes	N/A
	Cardiovascular disease	Yes	N/A	Yes	N/A
	Chronic renal disease	Yes	N/A	Yes	N/A
	Chronic liver disease	Yes	N/A	Yes	N/A
	Immunocompromised condition	Yes	N/A	Yes	N/A
	Neurologic/neurodevelopmental intellectual disability	Yes	N/A	Yes	N/A
	Other chronic diseases	Yes	N/A	Yes	N/A
	If female, currently pregnant	N/A	N/A	N/A	N/A
	Current smoker	Yes	N/A	Yes	N/A
	Former smoker	Yes	N/A	Yes	N/A
	Respiratory diagnostic testing test (respiratory virus testing panel information)	Yes	N/A	Yes	N/A
Specimens for COVID-19 testing
	Nasopharyngeal swab/oropharyngeal swab/sputum/other (specify)	N/A	N/A	N/A	N/A

^aELR: electronic laboratory reporting.

^bCCDA: consolidated clinical document architecture.

^cFHIR: Fast Healthcare Interoperability Resources.

^dCDC: Centers for Disease Control and Prevention.

^ePUI: Person Under Investigation.

^fIf notes are shared through FHIR.

^gN/A: not applicable.

^hADT: admission, discharge, and transfer.

ⁱICU: intensive care unit.