Table 2.
Baseline and procedural characteristics and 30-day outcomes of patients undergoing TTV repair with edge-to-edge devices.
| Edge-to-edge repair | ||||||
|---|---|---|---|---|---|---|
| MitraClip | TriClip | PASCAL | ||||
| Besler et al. | Mehr et al. | Ruf et al. | Nickenig et al. | Fam et al. | Kodali et al. | |
| (14) | (15) | (16) | (17) | (18) | (19) | |
| N of patients | 117 | 249 | 50 | 85 | 28 | 34 |
| Age | 79 | 79 | 80 (78–83) | 77.8 | 78 | 76.3 |
| STS-PROM score, % | 5.3 | NA | NA | NA | 4.6 ± 2.8 | 7.3 |
| Functional TR | 223 (89) | NA | 71 (84) | 29 (88) | ||
| TR severity | ||||||
| - None-/Moderate | 7 (6) | 8 (3) | 7 (14) | 5 (6) | 1 (3) | |
| - ≥Severe | 110 (94) | 241 (97) | 43 (86) | 80 (94) | 28 (100) | 32 (97) |
| Procedural outcomes | ||||||
| Procedural success | 95 (81) | 192 (77) | 50 (100) | 76 (91) | 24 (86) | 24 (80) |
| Number of devices | 2 ± 1 | 2 ± 1 | 1.7 ± 0.7 | 2.2 ± 0.8 | 1.4 ± 0.6 | 1.2 |
| Conversion to open surgery | NA | 1 (0.4) | 0 | 0 | 0 | NA |
| Device embolization or malposition | NA | NA | 0 | 0 | 0 | NA |
| 30-day outcomes | ||||||
| Mortality | 0 | 7 (2.8) | 0 | 0 | 2 (7.1) | 0 |
| Stroke | NA | 2 (0.8) | NA | 0 | 0 | 0 |
| Major or life-threatening bleeding | NA | 15 (6) | NA | 0 | 0 | 2 (5.9) |
| TR severity | ||||||
| - None-Moderate | 92 (78) | 192 (77) | 37 (54) | 73 (85.6) | 22 (85) | 14 (52) |
| - ≥Severe | 25 (22) | 57 (23) | 23 (46) | 12 (14.4) | 4 (15) | 13 (48) |
Continuous values are expressed as mean ± SD, mean (range) and median [interquartile range] as reported by authors. Categorical values are expressed as n (%).