. 2021 Apr 19;224(10):1765–1774. doi: 10.1093/infdis/jiab210

Table 4.

Model-based Mean Differences (95% CI) of Pre-ART Biomarker Concentrations for Participants Who Gained Weight Versus Maintained Weight

Pre-ART BMI Subgroup	IL-6, log₁₀ pg/mL	sTNF-RII, log₁₀ pg/mL	CXCL-10, log₁₀ pg/mL	sCD163, log₁₀ ng/mL	hsCRP, log₁₀ μg/mL
Normal weight	0.26 (.17 to .35)	0.12 (.07 to .16)	0.19 (.11 to .27)	0.08 (.02 to .14)	0.32 (.16 to .48)
Overweight	0.04 (−.06 to .13)	0.01 (−.05 to .06)	0.07 (−.02 to .15)	0.05 (−.02 to .11)	0.00 (−.32 to .03)
Obese	−0.08 (−.20 to .05)	−0.06 (−.13 to .01)	0.05 (−.06 to .16)	−0.05 (−.13 to .03)	−0.07 (−.29 to .16)

Models adjusted for sex, age (by decade), race/ethnicity, pre-ART viral load and CD4 cell count, and ART assignment. Bold text indicates a statistically significant comparison.

Abbreviations: ART, antiretroviral therapy; BMI, body mass index; CI, confidence interval; hsCRP, high-sensitivity C-reactive protein; IL-6, interleukin 6; sTNF-RII, soluble TNF-α receptor II.