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. 2022 Sep 28;17(9):e0275067. doi: 10.1371/journal.pone.0275067

Table 1. Study assessments during the inclusion period.

Assessments Before first experimental day Day 1 (First experimental day) Day 2 Day 8 (Second experimental day) Day 9
PSQI x
Sleep-wake evaluation x x x
KSS 0h, 1h, 2h, 3h, 4h, 5h 0h, 1h, 2h, 3h, 4h, 5h
Capillary ammonia 0h, 1h, 2h, 3h, 4h, 5h 0h, 1h, 2h, 3h, 4h, 5h
PHES 0h, 4h 0h, 4h
CRT 0h, 2h, 4h 0h, 2h, 4h
Pupillometry 0h, 3h, 5h 0h, 3h, 5h

PSQI, Pittsburgh Sleep Quality Index; KSS, Karolinska Sleepiness Scale; PHES, psychometric hepatic encephalopathy score; CRT, continuous reaction time