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. 2022 Sep 16;18(9):e1010539. doi: 10.1371/journal.pcbi.1010539

Table 1. Summary of the structure modeling results by DeepFold and the control methods on the 221 test proteins.

The p-values were calculated between DeepFold and the control methods using paired, two-sided Student’s t-tests.

Method TM-score (p-value) RMSD (p-value) Correct Folds* TMDeepFold > TMMethod
I-TASSER 0.383 (9.4E-80) 15.10 (7.1E-25) 24.0% 95.9%
C-I-TASSER 0.584 (1.8E-55) 8.89 (4.0E-26) 67.0% 95.9%
DMPfold 0.657 (5.6E-37) 7.81 (2.0E-18) 79.6% 92.3%
trRosetta 0.694 (8.3E-24) 6.81 (4.7E-09) 85.5% 87.8%
DeepFold 0.751 5.61 92.3% -

* This column represents the percent of proteins with TM-scores ≥0.5.

‡ This column indicates the percent of test proteins for which DeepFold generated a model with a higher TM-score than the control method.