TABLE 2.
Summary risk ratios of mortality before and after the introduction of MALDI‐TOF for identification of pathogen from blood cultures
| Category | Number of studies | Summary estimate (95% CI) | I 2 (95% CI) | Meta‐regression, p‐Value | Publication bias (Egger's test, p‐Value) |
|---|---|---|---|---|---|
| Mortality | 13 | 0.77 (0.66, 0.90) | 35.9 (0.0, 65.7) | NA | 0.227 |
| Reporting 28‐ or 30‐day mortality | 11 | 0.76 (0.64, 0.89) | 41.1 (0.0, 69.5) | 0.522 | 0.181 |
| Purely adult population | 9 | 0.69 (0.57, 0.84) | 37.1 (0.0, 69.8) | 0.103 | 0.269 |
| MALDI‐TOF with AST | 6 | 0.65 (0.49, 0.86) | 26.7 (0.0, 70.6) | 0.189 | 0.799 |
| MALDI‐TOF without AST | 5 | 0.77 (0.61, 0.98) | 44.9 (0.0, 78.3) | 0.947 | 0.424 |
Abbreviations: AST, antibiotic stewardship team; BSI, bloodstream infection; MALDI‐TOF, matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry.