Figure 4.

miR-194-5p knockdown partially reversed the inhibition of circFCHO2 silencing on the malignant phenotype of GC cells.

(A) Transfection efficiency of GC cells was explored by qRT-PCR. *** P < 0.001. (B) The proliferation ability of GC cells was researched by CCK-8 assay. (C) EDU staining was carried out to evaluate the proliferation ability of GC cells. (D) The invasion ability of GC cells was detected by transwell experiment. (E) The angiogenesis ability of GC cells was evaluated by tube formation experiment. (F) The cancer stem cell characteristics of GC cells was assessed by spheroidization experiment. ** P < 0.01 or *** P < 0.001 vs. sh-NC group. # P < 0.05 or ## P < 0.01 or ### P < 0.001 vs. sh-circFCHO2 group.