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. 2022 Sep 25;14(1):2121577. doi: 10.1080/19490976.2022.2121577

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Increase over the years in the proportion of cnf1-positive strains in E. coli ST131 H30Rx/C2. A) Distribution of fimH alleles (upper panel) or clades/subclades (lower panel) within the study population of E. coli ST131. Both figures show observed counts per year (dots) and data fitted lines (dashed lines) with a generalized linear model (Poisson regression). B) Increase of the proportion of cnf1-positive strains in the whole E. coli ST131 population along time (top panel, P = 7.41 10^–7) and by clades and subclades. The black dots represent the observed proportion of cnf1-positive strains by year with fitted line of a logistic regression model (blue curves). Dashed gray lines display the 95% confidence intervals. The P-values are not significant for clade A (P = 0.287), B (P = 0.952), H30R/C1 (P = 0.992) and significant for H30Rx/C2 (P = 1.25 10⁻¹¹).