Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 28;8(39):eabo3991. doi: 10.1126/sciadv.abo3991

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

This is an open-access article distributed under the terms of the Creative Commons Attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 4. — (A) Significant enrichment of BMI-associated GWAS SNVs in mDMRs and TOCs as computed by stratified LD score regression. Only enrichments remaining significant after Benjamini-Hochberg correction are shown. (B to D) Examples of overlaps between TOCs or mDMRs and NHGRI index SNVs associated with BMI. Human orthologs of mDMRs and TOCs (±1 kb) are indicated by vertical gray bars. Benjamini-Hochberg–adjusted P values for SNV-BMI associations obtained from (9). *P < 0.05, **P < 0.01, and ***P < 0.001.