Key resources table.

Reagent type (species) or resource	Designation	Source or reference	Identifiers	Additional information
Antibody	Anti-8-Hydroxy-2- deoxyguanosine (Mouse monoclonal)	Abcam	Cat#: ab48508	IF (1:200)
Antibody	Anti-8 iso Prostaglandin F2 alpha (Rabbit polyclonal)	Abcam	Cat#: ab2280	IF (1:200)
Antibody	Anti-DNP antibody (Rabbit polyclonal)	Sigma	Cat#: D9656	IF (1:200)
Antibody	Anti-MCT1 antibody (Mouse monoclonal)	Santa Cruz	Cat#: sc365501	IF (1:200)
Antibody	Anti-LDHA antibody (Rabbit monoclonal)	Cell Signaling	Cat#: 3582	IF (1:200)
Antibody	Anti-LDHB antibody (Mouse monoclonal)	Santa Cruz	Cat#: sc100775	IF (1:200)
Antibody	Goat anti-Rabbit (goat polyclonal, Alexa Fluor conjugate)	Abcam	Cat#: ab150077	IF (1:200)
Antibody	Donkey anti-Rabbit (donkey polyclonal, Alexa Fluor conjugate)	Abcam	Cat#: ab150075	IF (1:200)
Antibody	Goat anti-Mouse (goat polyclonal, Alexa Fluor conjugate)	Abcam	Cat#: ab150113	IF (1:200)
Biological sample (mouse)	Blastocyst	This paper		Female
Biological sample (mouse)	Liver	This paper		Male/Female
Biological sample (mouse)	Muscle	This paper		Male/Female
Biological sample (mouse)	Fat	This paper		Male/Female
Commercial assay or kit	Seahorse XF Cell Mito Stress Test kit	Agilent	103010–100
Commercial assay or kit	Seahorse XF Glycolysis Stress Test kit	Agilent	103020–100
Commercial assay or kit	Pyruvate assay kit	Cayman	Cat#: 700470
Commercial assay or kit	Lactate assay kit	Cayman	Cat#: 700510
Commercial assay or kit	NAD Quantitation kit	Sigma	Cat#: MAK037
Chemical compound, drug	SNARF-1	Thermo fisher	Cat#: C1272
Software, algorithm	GraphPad Prism	GraphPad
Strain, strain background (mouse)	CF-1	ENVIGO	Hsd:NSA	Oocyte donor
Strain, strain background (mouse)	B6D2F1	The Jackson Laboratory	100006	Sperm donor