Table 3:
Median and interquartile range of the extracted gas-transfer map means and standard deviations for the pediatric cohorts. Significant differences are in bold. P-values are reported with respect to the pediatric healthy cohort.
| Median [IQR] (P-value) | Ped. Healthy N = 5 | BMT N = 12 | BPD N = 4 | CF N = 8 | chILD N = 5 | |
|---|---|---|---|---|---|---|
|
| ||||||
| Ventilation | Mean | 0.75 [0.74–0.76] |
0.69
[0.66–0.72] (0.002) |
0.73 [0.72–0.75] (0.071) |
0.69
[0.64–0.74] (0.014) |
0.70 [0.66–0.74] (0.059) |
| Std. Dev. | 0.14 [0.13–0.14] |
0.17
[0.16–0.17] (0.003) |
0.13 [0.12–0.14] (0.500) |
0.18
[0.15–0.21] (0.004) |
0.15
[0.14–0.15] (0.038) |
|
| Dissolved (×10−3) |
Mean | 9.06 [8.30–9.52] |
11.39 [7.43–16.87] (0.123) |
6.34
[5.02–7.82] (0.014) |
11.50
[9.66–16.18] (0.029) |
8.76 [6.94–11.84] (0.458) |
| Std. Dev. | 1.32 [0.77–1.56] |
1.84
[1.23–2.20] (0.046) |
0.83 [0.50–1.27] (0.164) |
1.75
[1.21–2.00] (0.039) |
1.65 [0.86–2.43] (0.301) |
|
| Barrier-uptake (×10−3) |
Mean | 8.17 [7.89–9.35] |
10.88 [7.04–16.17] (0.146) |
5.81
[4.74–7.24] (0.014) |
10.88 [9.14–15.07] (0.054) |
8.49 [6.53–11.64] (0.458) |
| Std. Dev. | 1.30 [0.76–1.59] |
1.72
[1.23–2.25] (0.046) |
0.82 [0.50–1.21] (0.231) |
1.66 [1.15–1.99] (0.072) |
1.68 [0.89–2.42] (0.125) |
|
| RBC-transfer (×10−3) |
Mean | 2.13 [2.12–2.74] |
2.58 [1.78–3.84] (0.337) |
2.26 [1.44–2.74] (0.231) |
3.36
[2.90–4.94] (0.029) |
2.01 [1.18–2.49] (0.125) |
| Std. Dev. | 0.62 [0.56–0.74] |
0.90 [0.61–1.17] (0.070) |
0.51 [0.42–0.56] (0.071) |
0.79 [0.66–0.96] (0.054) |
0.73 [0.51–0.86] (0.377) |
|
| RBC:Barrier | Mean | 0.29 [0.26–0.32] |
0.24 [0.17–0.42] (0.230) |
0.34 [0.30–0.44] (0.071) |
0.31 [0.29–0.37] (0.232) |
0.24 [0.14–0.31] (0.087) |
| Std. Dev. | 0.09 [0.07–0.09] |
0.09 [0.06–1.14] (0.417) |
0.09 [0.07–1.08] (0.312) |
0.08 [0.07–0.91] (0.442) |
0.10 [0.08–1.03] (0.232) |
|