Skip to main content
. 2022 Sep 6;99(10):e1067–e1078. doi: 10.1212/WNL.0000000000200832

Figure 1. Neuropathologic Associations in the 90+ Study Cohort.

Figure 1

Spearman rank-order correlations between individual neuropathologic scores (***p < 0.0001, **p < 0.01, and *p < 0.05) (A) and associations between individual neuropathologic lesion types and cognitive test scores, based on separate multiple linear regression analyses, with cognitive test score as the dependent variable and lesion type as the predictor, controlling for age at visit, interval between visit and death, gender, and education. Standardized β coefficients are reported to facilitate cross-measure comparison. Asterisks represent statistical significance after correcting for multiple comparisons (B). 3MS = Modified Mini-Mental State Examination; Aβ = β-amyloid; CAA = cerebral amyloid angiopathy; CVLT-II = California Verbal Learning Test-II; HS = hippocampal sclerosis; LATE-NC = limbic-predominant age-related TDP-43 encephalopathy neuropathologic change; LBD = Lewy body disease; μVBI = microvascular brain injury; MMSE = Mini-Mental State Examination; NFT = neurofibrillary tangle; NIA-AA = National Institute on Aging-Alzheimer Association.