Figure 1. Intended Use of the Model in a Stroke Workflow.

IVT = IV thrombolysis; ML = machine learning; mRS = modified Rankin scale; MT = mechanical thrombectomy. The ML model outputs a probability (risk score) for mRS 5–6 based on variables available ahead of recanalization therapies. This information is provided to the treating physicians after selection of patient for recanalization and could serve as a marker for futile recanalization. Workflow derived from Meier et al. with permission.²⁹