Table 3. Effect of change in prevalence on various diagnostic indices of test X.

Prevalence (%)	Sensitivity	Specificity	LR+	LR–	PPV	NPV	Accuracy
20	86.25	79.17	4.14	0.17	50.86	95.84	80.58
30	86.25	79.17	4.14	0.17	63.95	93.07	81.29
40	86.25	79.17	4.14	0.17	73.40	89.62	82.00
50	86.25	79.17	4.14	0.17	80.54	85.20	82.71
60	86.25	79.17	4.14	0.17	86.13	79.33	83.42

Abbreviations: LR, likelihood ratio; NPV, negative predictive value; PPV, positive predictive value.