Table II.
Characteristics/Outcomes | Unvaccinated |
Partially |
Fully |
P∗ | P† |
---|---|---|---|---|---|
2848 (100) | 459 (100) | 398 (100) | |||
Age (y) | |||||
Mean (SD) | 16.4 (2.3) | 16.6 (2.0) | 17.4 (2.0) | <.0001 | |
Age group (y) | |||||
12-15 | 2664 (46.2) | 575 (37.8) | 314 (26.7) | <.0001 | <.0001 |
16-17 | 1519 (26.4) | 396 (26.0) | 271 (23.0) | ||
18-19 | 1577 (27.4) | 551 (36.2) | 591 (50.3) | ||
Period of admission‡ | |||||
Gamma/Delta | 2062 (72.4) | 179 (39.0) | 41 (10.3) | <.0001 | <.0001 |
Omicron | 786 (27.6) | 280 (61.0) | 357 (89.7) | ||
Sex | |||||
Male | 1505 (52.8) | 277 (60.3) | 263 (66.1) | <.0001 | <.0001 |
Female | 1343 (47.2) | 182 (39.7) | 135 (33.9) | ||
Region | |||||
Southeast | 1336 (46.9) | 211 (46.0) | 210 (52.8) | <.0001 | .009 |
South | 575 (20.2) | 91 (19.8) | 84 (21.1) | ||
Central-West | 307 (10.8) | 44 (9.6) | 27 (6.8) | ||
Northeast | 393 (13.8) | 66 (14.4) | 57 (14.3) | ||
North | 237 (8.3) | 47 (10.2) | 20 (5.0) | ||
Ethinicity§ | |||||
White | 1214 (51.8) | 220 (52.9) | 184 (56.4) | .22 | .21 |
Brown Black | 1093 (46.6) | 184 (44.2) | 137 (42.0) | ||
Asian | 21 (0.9) | 7 (1.7) | 1 (0.3) | ||
Indigenous | 17 (0.7) | 5 (1.2) | 4 (1.2) | ||
Signs/symptoms at presentation | |||||
Fever | 1734 (60.9) | 268 (58.4) | 197 (49.5) | <.0001 | <.0001 |
Cough | 1814 (63.7) | 258 (56.2) | 227 (57.0) | .001 | .03 |
Dyspneia | 1438 (50.5) | 180 (39.2) | 146 (36.7) | <.0001 | <.0001 |
Gastrointestinal | 327 (11.5) | 53 (11.5) | 27 (6.8) | .02 | .85 |
Number of comorbidities | |||||
None | 2159 (75.8) | 335 (73.0) | 300 (75.4) | .76 | .96 |
1 | 606 (21.3) | 108 (23.5) | 87 (21.9) | ||
2 | 83 (2.9) | 16 (3.5) | 11 (2.8) | ||
Oxygen saturation <95%§ | |||||
Yes | 1210 (54.5) | 137 (39.8) | 118 (41.4) | <.0001 | <.0001 |
ICU | |||||
Yes | 820 (28.8) | 116 (25.3) | 85 (21.4) | .004 | .03 |
Ventilatory support§ | |||||
None | 1473 (56.2) | 284 (68.4) | 286 (72.6) | ||
Noninvasive | 855 (32.6) | 88 (21.2) | 72(18.3) | <.0001 | <.0001 |
Invasive | 292 (11.1) | 43 (10.4) | 36 (9.1) | ||
Severity index¶ | |||||
Mild | 1190 (41.8) | 248 (54.0) | 222 (55.8) | ||
Moderate | 1278 (44.9) | 152 (33.1) | 132 (33.2) | <.0001 | <.0001 |
Severe | 380 (13.3) | 59 (12.9) | 44 (11.1) | ||
Outcomes§ | |||||
Discharge | 2511 (89.6) | 397 (88.4) | 352 (88.4) | ||
Death | 194 (6.9) | 30 (6.7) | 16 (4.0) | .001 | <.0001 |
In-hospital | 97 (3.5) | 22 (4.9) | 30 (7.5) |
P, comparison among of 3 groups.
P, comparison between unvaccinated/partially vs fully vaccinated groups.
Gamma/Delta predominance (June 25, 2021, to December 24, 2021) and Omicron predominance (December 25, 2021, to March 28, 2022).
Missing data: Ethnicity, 618; Oxygen saturation, 855; Ventilatory support, 276; Outcomes, 56.
Severity index: mild (no need of oxygen support and no admission ICU), moderate (need of noninvasive oxygen support and admission in ICU), and severe (mechanical ventilation or death).