Table 2.
Details of LCH organ system involvement by age at LCH.
| Age at LCH diagnosis |
|||
|---|---|---|---|
| Disease category | ≤18 years | >18 years | Total |
| Single-system | 53 (45.7)1 | 125 (81.2)2 | 178 (65.9) |
| Bone | 39 | 7 | 46 |
| Skin | 9 | 21 | 30 |
| Lymph | 2 | 34 | 36 |
| Lungs | 2 | 52 | 54 |
| Thyroid | - | 4 | 4 |
| Urinary tract-Genital organs | - | 2 | 2 |
| Liver | - | 1 | 1 |
| Oral Soft tissue | - | 1 | 1 |
| Gastro-intestinal | - | 1 | 1 |
| Other | 1 | 2 | 3 |
| Multi-system | 61 (52.6)3 | 29 (18.8)4 | 90 (33.3) |
| Total systems | 209 | 71 | 280 |
| Bone | 47 | 8 | 55 |
| Skin | 42 | 14 | 56 |
| Lymph | 24 | 13 | 37 |
| Liver | 21 | 2 | 23 |
| Lungs | 19 | 13 | 32 |
| Bone marrow | 16 | 7 | 23 |
| Spleen | 15 | 4 | 19 |
| Oral soft tissue | 7 | 2 | 9 |
| Other soft tissue | 5 | 3 | 8 |
| CNS | 4 | 2 | 6 |
| Ear | 3 | - | 3 |
| Gastro-intestinal | 1 | - | 1 |
| Other | 5 | 3 | 8 |
| Unknown | 2 (1.7) | 0 | 2 (0.7) |
| Total LCH | 116 | 154 | 270 |
1,2
1 case of diabetes insipidus.
3
12 cases of diabetes insipidus.
4
2 cases of diabetes insipidus.