Fig. 6.

Effects of QCS/HA/LAP coating on WNT16/β-catenin axis in vivo. (A) H&E and Masson staining results of peri-implant tissues in various groups at 6 and 12 weeks. (B) IF staining of WNT16 (red), β-catenin (green), and DAPI (blue) of the surrounding bone marrow cells at 6 and 12 weeks. (C–F) IHC-staining and related quantification of Collagen-1 and OCN in regenerative tissue around the implants (red dotted line indicated ROI). Data are presented as mean ± SD. Significant differences among groups are indicated (**p < 0.01).