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. 2022 Sep 26;7(10):1525–1535. doi: 10.1038/s41564-022-01213-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — a, Heatmap of all samples (n = 1431) showing the relative abundance of the most dominant species, coloured by phyla, stratified by PGCT. b, Box plots showing the alpha diversity (richness and Shannon diversity) for each PGCT. The centre line denotes the median, the box limits denote the inter-quartile range (IQR) and whiskers extend to the limits. c, LEfSe identifying discriminatory features of each PGCT based on Linear Discriminant Analysis (LDA). Coloured bars denote PGCTs.