Figure 1.

Flowchart of the participants selection.

(A) Individuals in the UK Biobank cohort were excluded if they had reported dementia at baseline, stroke at baseline, or without follow-up records. The remaining participants were classified based on their first reported years of dementia or AD after baseline.

(B) Left: distribution of observation times for the derived study population, whose median observation times were 11.9 years (IQR 11.2-12.5). Middle: distribution of first reported years of dementia after baseline. Right: distribution of first reported years of AD after baseline.

Abbreviations: AD = Alzheimer's Disease