Table 3.
Reported studies on the compounds and beneficial effects of natural sweeteners.
| Natural sweeteners | Compounds | Reported Health Benefits Inhibiting Toxicity and Adverse Reaction Issues | References |
|---|---|---|---|
| Date palm | Dietary fiber, minerals, carotenoids, vitamins and polyphenols | Cell biology techniques were used in a study to demonstrate date palm polyphenols that inhibited hIAPP and prevented T2DM Reduced cytotoxicity and aggregation |
(Chaari et al., 2020) |
| Grapes | Flavonoids, fructose, pectin, proanthocyanidin | A study on rats reveals that grapes inhibited myocardial infarction and prevented lung, breast and gastric adenocarcinoma cells Combat the free radicals to avoid oxidative stress |
(Bagchi et al., 2000) |
| Honey | Niacin, water, riboflavin, potassium, copper, trace amounts of vitamins | MSA mice were fed with 10% honey and the result demonstrated the prevention of mycotoxins genotoxicity for two months Enhanced the gut microflora to provide antigenotoxicity and detoxification |
(Ezz El-Arab, Girgis, Hegazy, El-Khalek and Azzat, 2006) |
| Sorghum | Bioactive compounds, polyphenols | Antioxidant activity prevents the risk of several cancers, decreases the availability of calories and reduces weight gain, hence preventing obesity, cardiovascular diseases and cancer effectively | (Awika and Rooney, 2004) |
| Sugar-cane | Vitamin A, Vitamin B Complex, minerals | A research study on FW rats revealed OARC and antioxidant properties Inhibited peroxidation of lipid, scavenge free radicals and prevent iron complex |
(Kadam et al., 2008) |
| Beetroot | Betalains, bioactive compounds, | In vivo and in vitro trials showed anti-inflammatory, anti-oxidative and chemo-preventive action | (Clifford et al., 2015) |
| Jaggery | Vitamins, Magnesium, calcium, zinc | MSA mice were fed with jaggery (250mg/mice) to determine the antioxidant effect for 180 days Prevented the DNA damage, showed degenerative and necrosis alternations in bronchiolar epithelium |
(N. Singh, Kumar, Lal, Raisuddin and Sahu, 2010) |
| Coconut | Iron, calcium, zinc and potassium, polyphenols and antioxidant | Prevent gum disease, diabetes development and heart disease and several other serious health issues | (Trinidad, 2003) |
hIAPP = human Islet Amyloid Polypeptide, T2DM = Type-2 diabetes mellitus, MSA = Male Swiss albino, FW = Female Wistar, OARC = oxygen radical absorbance capacity.